Dynamics of Glomerular Ultrafiltration in the Rat. IV. DETERMINATION OF THE ULTRAFILTRATION COEFFICIENT
نویسندگان
چکیده
منابع مشابه
Dynamics of glomerular ultrafiltration in the rat. IV. Determination of the ultrafiltration coefficient.
Pressures and flow rates were measured in accessible surface glomeruli of mutant Wistar rats under conditions deliberately designed to prevent achievement of filtration pressure equilibrium, that is, the equalization of transcapillary hydrostatic and oncotic pressures by the efferent end of the glomerulus as typically observed in the normal hydropenic rat. Disequilibrium was obtained at elevate...
متن کاملDynamics of glomerular ultrafiltration in the rat.
This study was undertaken in an effort to examine the effects of selective variations in systemic hematocrit on the preglomerular. glomerular. and postglomerular microcirculation in the rat. By isovolemic exchange transfusions, systemic hematocrit (control 51 ml/ 100 ml) was either reduced (21 ml/100 ml, N = 7 rats) or elevated (62 ml/100 ml, N = 7). Single nephron glomerular filtration rate va...
متن کاملDynamics of Glomerular Ultrafiltration in the Rat
This study was undertaken in an effort to examine the effects of selective variations in systemic hematocrit on the preglomerular. glomerular. and postglomerular microcirculation in the rat. By isovolemic exchange transfusions, systemic hematocrit (control 51 ml/ 100 ml) was either reduced (21 ml/100 ml, N = 7 rats) or elevated (62 ml/100 ml, N = 7). Single nephron glomerular filtration rate va...
متن کاملEffect of mannitol on glomerular ultrafiltration in the hydropenic rat.
The effect of mannitol upon glomerular ultrafiltration was examined in hydropenic Munich-Wistar rats. Superficial nephron filtration rate (sngfr) rose from 32.0+/-0.9 nl/min/g kidney wt to 42.0+/-1.6 (P < 0.001) in eight rats. Hydrostatic pressure gradients acting across the glomerular capillary (DeltaP) were measured in glomerular capillaries and Bowman's space with a servo-nulling device, sys...
متن کاملA model of glomerular ultrafiltration in the rat.
DEEN, W. M., C. R. ROBERTSON, AND B. M. BRENNER. A model of glomerular ultrajltration in the rat. Am. J. Physiol. 223(5) : 1178-l 183. 1972.-A mathematical model has been developed to investigate the influence of a number of physiological variables on the net driving pressure for ultrafiltration (PuF) in the rat glomerulus. The model was used to predict osmotic pressure differences as functions...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1973
ISSN: 0021-9738
DOI: 10.1172/jci107324